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- If the lumen of appendix slowly become completely occluded, usually by a fibrous stricture and pent-up secretion (mucus) remain sterile mucocele result, if infection supervenes, an empyema results.
- Appendix enlarges several times in its size and present as appendicitis or as a painless mass.
- Perforation may results in pseudomyxoma peritonei
- Appendicectomy is curative if the lesion is benign but in cases of neoplastic lesions (cystadenoma and cystadenocarcinoma) may be cause of mucocele, right hemicolectomy is indicated.